Internal Medicine Resident Physician Temple University Hospital Temple University Hospital Philadelphia, Pennsylvania, United States
Disclosure(s):
Jillian Hall, MD: No financial relationships to disclose
Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has shown to be a viable form of temporary mechanical circulatory support for refractory cardiogenic shock. Outcome data among diverse patient populations is limited. We present a retrospective review of patients cannulated on VA-ECMO in a diverse patient population to investigate mortality outcomes by demographics.
Methods: A retrospective review of patients cannulated and supported on VA-ECMO from 2020-2024 at Temple University Hospital was conducted. Inclusion criteria included patients that were cannulated in the emergency room, intensive care unit, or cardiac catheterization lab. Patients that were placed on VA-ECMO during a surgical procedure and those that were cannulated at an outside hospital were excluded. Demographic information was collected and descriptive statistics were utilized. Chi Square analysis was used for demographic differences in mortality.
Outcome: There were 143 patients placed on VA-ECMO from 2020-2024.Out of the 143 patients, 100 (70%) were male and 43 (30%) were female with a mean age of 55 ± 14 years (median 58 years, range 18-83 years). Of these patients, 69 (48%) identified as Black, 55 (39%) as White Non-Hispanic, 17 (12%) as Hispanic, and 2 (1%) as Other. Regarding indication for ECMO, 77 (54%) were after cardiac arrest, 50 (35%) were for non-myocardial infarction (MI) cardiogenic shock, and 16 (11%) were for MI cardiogenic shock. Average time on ECMO was 146 ± 164 hours (median 100 hours, range 1-1152 hours) Thirty-day post discharge survival was 31% (51 patients). There was no difference in mortality between sex (p=0.61) or race/ethnicity (p=0.06).
Conclusion: There was no significant difference in mortality among sex or race/ethnicity. More outcome data is needed to address possible disparities in refractory cardiogenic shock requiring mechanical circulatory support.